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Sub-neutralizing concentrations of Zika virus IgM monoclonal antibodies reduce IgG-mediated antibody-dependent enhancement of infectivity

2026-01-03

Abstract excerpt

<h4>Summary</h4> Zika virus (ZIKV) is an arthropod-borne flavivirus endemic to Latin America and Africa for which IgG-mediated antibody-dependent enhancement of infectivity (ADE) is a phenomenon of concern. The interplay dynamics between flavivirus-specific antibodies of the IgG and IgM isotypes are mostly unknown. Here, we used DH1017.IgM, a previously described human-derived, pentameric, ultrapotent neutralizin...

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Literature Corpus work
7eef8820-add6-54f9-bff9-9e24b4c4aa96
DOI
10.64898/2026.01.03.697490
Open publication

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Sub-neutralizing concentrations of Zika virus IgM monoclonal antibodies reduce IgG-mediated antibody-dependent enhancement of infectivityDOI 10.64898/2026.01.03.697490
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