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Article

Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding.

Cell metabolism - 1 Aug 2008

Greer Elisabeth R, Pérez Carissa L, Van Gilst Marc R, Lee Brian H, Ashrafi Kaveh

Abstract excerpt

A major challenge in understanding energy balance is deciphering the neural and molecular circuits that govern behavioral, physiological, and metabolic responses of animals to fluctuating environmental conditions. The neurally expressed TGF-beta ligand DAF-7 functions as a gauge of environmental conditions to modulate energy balance in C. elegans. We show that daf-7 signaling regulates fat metabolism and feeding...

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Identifiers

PMID: 18680713
DOI: 10.1016/j.cmet.2008.06.005
PMCID: PMC2556218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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