Article
Coordinated regulation of foraging and metabolism in C. elegans by RFamide neuropeptide signaling.
Cell metabolism - 1 Apr 2009
Cohen Merav, Reale Vincenzina, Olofsson Birgitta, Knights Andrew, Evans Peter, de Bono Mario
Abstract excerpt
Animals modify food-seeking behavior and metabolism according to perceived food availability. Here we show that, in the roundworm C. elegans, release of neuropeptides from interneurons that are directly postsynaptic to olfactory, gustatory, and thermosensory neurons coordinately regulates behavior and metabolism. Animals lacking these neuropeptides, encoded by the flp-18 gene, are defective in chemosensation and...
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