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Article

Feeding state, insulin and NPR-1 modulate chemoreceptor gene expression via integration of sensory and circuit inputs.

PLoS genetics - 1 Oct 2014

Gruner Matthew, Nelson Dru, Winbush Ari, Hintz Rebecca, Ryu Leesun, Chung Samuel H, Kim Kyuhyung, Gabel Chrisopher V, van der Linden Alexander M

Abstract excerpt

Feeding state and food availability can dramatically alter an animals' sensory response to chemicals in its environment. Dynamic changes in the expression of chemoreceptor genes may underlie some of these food and state-dependent changes in chemosensory behavior, but the mechanisms underlying these expression changes are unknown. Here, we identified a KIN-29 (SIK)-dependent chemoreceptor, srh-234, in C. elegans...

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Source

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Identifiers

PMID: 25357003
DOI: 10.1371/journal.pgen.1004707
PMCID: PMC4214617

Genes

KIN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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