Article
An unexpected RNA distal interaction mode found in an essential region of the hepatitis C virus genome.
Nucleic acids research - 4 May 2018
Cantero-Camacho Ángel, Gallego José
Abstract excerpt
The 3'X tail is a functionally essential 98-nt sequence located at the 3'-end of the hepatitis C virus (HCV) RNA genome. The domain contains two absolutely conserved dimer linkage sequence (DLS) and k nucleotide segments involved in viral RNA dimerization and in a distal base-pairing interaction with stem-loop 5BSL3.2, respectively. We have previously shown that domain 3'X forms an elongated structure comprising...
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