MeCP2 as an Activator of Gene Expression.

Abstract excerpt

Rett syndrome is a neurodevelopmental disorder that primarily affects females and is caused by mutations in the methyl-CpG-binding-protein 2 (MECP2) gene. Initially, MeCP2 had been shown to be a repressor of gene transcription. In their 2008 paper, Chahrour and colleagues (DOI: 10.1126/science.1153252) reported that MeCP2 could also function as a transcriptional activator.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Expression
• Share to MECP2 gene
• Share to Genetic Predisposition to Disease