Topological analysis of DPY19L3, a human C-mannosyltransferase.

Abstract excerpt

C-mannosylation is a rare type of protein glycosylation, the functions and mechanisms of which remain unclear. Recently, we identified DPY19L3 as a C-mannosyltransferase of R-spondin1 in human cells. DPY19L3 is predicted to be a multipass transmembrane protein that localizes to the endoplasmic reticulum (ER); however, its structure is undetermined. In this study, we propose a topological structure of DPY19L3 by...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Asparagine
• Share to Computer Simulation
• Share to Endoplasmic Reticulum