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Article

HIV-1 Nef CAWLEAQ motif: a regulator of monocytes invasion through ENO1 modulation.

Molecular and cellular biochemistry - 1 Oct 2018

Saxena Reshu, Vekariya Umesh Kumar, Kumar Pradeep, Tripathi Amit Kumar, Ghosh Jimut Kanti, Tripathi Raj Kamal

Abstract excerpt

HIV-1 transmission and spread involves significant host-virus interaction. Possible targets for obstacle of HIV-1 lie at the site of mucosal barriers. Thus a better understanding of how HIV-1 infects target cells at such sites and leads their invasion is required, with prime focus on the host determinants regulating HIV-1 spread. For the viral infectivity and pathogenicity, HIV-1 Nef facilitates immune evasion...

Read the complete abstract on PubMed

Topics

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Share to Amino Acid Motifs
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Monocytes

Share to nef Gene Products, Human Immunodeficiency Virus

Share to Phosphopyruvate Hydratase

Share to THP-1 Cells

Share to Tumor Suppressor Proteins

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Source

Identifiers

PMID: 29404888
DOI: 10.1007/s11010-018-3300-5

Genes

ENO1
VDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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