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Article

High frequency of type 2 diabetes and impaired glucose tolerance in Japanese subjects with the angiopoietin-like protein 8 R59W variant.

Journal of clinical lipidology - 1 Jan 2000

Liu Jianhui, Yagi Kunimasa, Nohara Atsushi, Chujo Daisuke, Ohbatake Azusa, Fujimoto Aya, Miyamoto Yukiko, Kobayashi Junji, Yamagishi Masakazu

Abstract excerpt

BACKGROUND: Angiopoietin-like protein 8 (ANGPTL8) is considered to be metabolically multifunctional. One notable function still to be elucidated definitively is a betatrophic role in protecting and preserving pancreatic beta-cell function. There is, however, a paucity of data regarding the role of ANGPTL8 in the etiology of type 2 diabetes (T2D), but some findings of human research have suggested the potential...

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Share to Angiopoietin-like Proteins
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose Intolerance

Share to Hypertriglyceridemia

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Share to Mutation, Missense

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Source

Identifiers

PMID: 29397342
DOI: 10.1016/j.jacl.2017.12.011

Genes

ANGPTL8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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