Article
ANGPTL8/Betatrophin R59W variant is associated with higher glucose level in non-diabetic Arabs living in Kuwaits.
Lipids in health and disease - 11 Feb 2016
Abu-Farha Mohamed, Melhem Motasem, Abubaker Jehad, Behbehani Kazem, Alsmadi Osama, Elkum Naser
Abstract excerpt
BACKGROUND: ANGPTL8 (betatrophin) has been recently identified as a regulator of lipid metabolism through its interaction with ANGPTL3. A sequence variant in ANGPTL8 has been shown to associate with lower level of Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). The objective of this study is to identify sequence variants in ANGPTL8 gene in Arabs and investigate their association with ANGPTL8...
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