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Article

Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations.

Human molecular genetics - 1 Jun 2007

Meirhaeghe Aline, Sandhu Manjinder S, McCarthy Mark I, de Groote Pascal, Cottel Dominique, Arveiler Dominique, Ferrières Jean, Groves Christopher J, Hattersley Andrew T, Hitman Graham A, Walker Mark, Wareham Nicholas J, Amouyel Philippe

Abstract excerpt

Brain natriuretic peptide (BNP/NPPB) is a member of the natriuretic family involved in the regulation of blood pressure and blood volume as well as lipolysis control in human fat cells. Thus BNP may play a role in energy metabolism and metabolic diseases. We therefore assessed the association between the BNP promoter T-381C polymorphism and risk of type 2 diabetes and metabolic and BNP expression traits in...

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PMID: 17412758
DOI: 10.1093/hmg/ddm084

Genes

NPPB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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