Article
Gender differences in the association of gene polymorphisms with type 2 diabetes mellitus.
International journal of molecular medicine - 1 Apr 2007
Yamaguchi Sachiyo, Yamada Yoshiji, Matsuo Hitoshi, Segawa Tomonori, Watanabe Sachiro, Kato Kimihiko, Yokoi Kiyoshi, Ichihara Sahoko, Metoki Norifumi, Yoshida Hidemi, Satoh Kei, Nozawa Yoshinori
Abstract excerpt
Type 2 diabetes mellitus is a complex metabolic disorder in which endogenous sex hormones may contribute to sex-dependent etiologies. We hypothesized that genetic variants related to type 2 diabetes mellitus might differ between men and women. We thus performed a large-scale association study to identify gene polymorphisms associated with type 2 diabetes mellitus in men and women separately. The study population...
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