Article
Exploring epistatic relationships of NO biosynthesis pathway genes in susceptibility to CHD.
Acta pharmacologica Sinica - 1 Jul 2010
Tu Yuan-chao, Ding Hu, Wang Xiao-jing, Xu Yu-jun, Zhang Lan, Huang Cong-xin, Wang Dao-wen
Abstract excerpt
AIM: To assess the epistatic relationships of nitric oxide (NO) biosynthesis pathway genes in susceptibility to coronary heart disease (CHD). METHODS: A total of 2142 subjects enrolled in two case-control studies was genotyped for 7 single-nucleotide polymorphisms (SNP) within NO biosynthesis pathway genes using TaqMan assays. The association analyses were performed at both SNP and haplotype levels. Two-way...
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