Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epistasis analysis for estrogen metabolic and signaling pathway genes on young ischemic stroke patients.

PloS one - 1 Jan 2012

Hsieh Yi-Chen, Jeng Jiann-Shing, Lin Huey-Juan, Hu Chaur-Jong, Yu Chia-Chen, Lien Li-Ming, Peng Giia-Sheun, Chen Chin-I, Tang Sung-Chun, Chi Nai-Fang, Tseng Hung-Pin, Chern Chang-Ming, Hsieh Fang-I, Bai Chyi-Huey, Chen Yi-Rhu, Chiou Hung-Yi

Abstract excerpt

BACKGROUND: Endogenous estrogens play an important role in the overall cardiocirculatory system. However, there are no studies exploring the hormone metabolism and signaling pathway genes together on ischemic stroke, including sulfotransferase family 1E (SULT1E1), catechol-O-methyl-transferase (C...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Ischemia
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to Estrogen Receptor alpha

Share to Estrogens

Share to Signal Transduction

Share to Stroke

Share to Sulfotransferases

Source

Open in PubMed Open full text

Identifiers

PMID: 23112845
DOI: 10.1371/journal.pone.0047773
PMCID: PMC3480403

Genes

COMT
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23112845-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epistasis analysis for estrogen metabolic and signaling pathway genes on young ischemic stroke patients.PMID 23112845Read ↗

Interaction among CYP2C8, EPHX2, and CYP4A11 Gene Variants Significantly Increases the Risk for Ischemic Stroke in Chinese Populations.Semantic proximity Read ↗

Genetic polymorphisms of ALOX5AP and CYP3A5 increase susceptibility to ischemic stroke and are associated with atherothrombotic events in stroke patients.Semantic proximity Read ↗

CYP2C8 rs17110453 and EPHX2 rs751141 two-locus interaction increases susceptibility to ischemic stroke.Semantic proximity Read ↗

COC use and ESR1 genetic variants associated with the risk of strokeSemantic proximity Read ↗

The association of CYP1A1 genetic polymorphisms and additional gene-gene interaction with ischemic stroke in the eastern Han of China.Semantic proximity Read ↗

Interaction between ALOX5AP and CYP3A5 gene variants significantly increases the risk for cerebral infarctions in Chinese.Semantic proximity Read ↗

Association between estrogen receptor alpha c.454-397T>C and c.454-351A>G and ischemic stroke risk: a systematic review and meta-analysis.Semantic proximity Read ↗

Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer.Semantic proximity Read ↗

ESR2 Genetic Variants and Combined Oral Contraceptive Use Associated with the Risk of Stroke.Semantic proximity Read ↗

Interaction Between CYP4F2 rs2108622 and CPY4A11 rs9333025 Variants Is Significantly Correlated with Susceptibility to Ischemic Stroke and 20-Hydroxyeicosatetraenoic Acid Level.Semantic proximity Read ↗

Estrogen receptor alpha gene variation and the risk of stroke.Semantic proximity Read ↗

Association of Estrogen Receptor-α and Aryl Hydrocarbon Receptor Gene Polymorphisms with Ischemic Stroke in an Egyptian Population: A Pilot Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.