Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer.

PloS one - 1 Jan 2018

He Yanjing, Penney Michelle E, Negandhi Amit A, Parfrey Patrick S, Savas Sevtap, Yilmaz Yildiz E

Abstract excerpt

BACKGROUND: Metastasis is a major cause of mortality in cancer. Identifying prognostic factors that distinguish patients who will experience metastasis in the short-term and those that will be free of metastasis in the long-term is of particular interest in current medical research. The objective of this study was to examine if select genetic polymorphisms can differentiate colorectal cancer patients based on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to TYMS gene

Share to Methionine

Share to Neoplasm Metastasis

Share to Polymorphism, Single Nucleotide

Share to Threonine

Share to Thymidylate Synthase

Source

Open in PubMed Open full text

Identifiers

PMID: 29394274
DOI: 10.1371/journal.pone.0192316
PMCID: PMC5796722

Genes

TYMS
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer.PMID 29394274Read ↗

Integrating TYMS, KRAS and BRAF testing in patients with metastatic colorectal cancer.Semantic proximity Read ↗

The long-term survival characteristics of a cohort of colorectal cancer patients and baseline variables associated with survival outcomes with or without time-varying effectsSemantic proximity Read ↗

SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer.Semantic proximity Read ↗

Single nucleotide polymorphisms in the metastasis-associated in colon cancer-1 gene predict the recurrence of hepatocellular carcinoma after transplantation.Semantic proximity Read ↗

The TYMS-TSER polymorphism is associated with toxicity of low-dose capecitabine in patients with advanced gastrointestinal cancer.Semantic proximity Read ↗

Genetic variations are associated with lymph node metastasis in colorectal cancer patients.Semantic proximity Read ↗

Long Survival and Severe Toxicity Under 5-Fluorouracil-Based Therapy in a Patient With Colorectal Cancer Who Harbors a Germline Codon-Stop Mutation in TYMS.Semantic proximity Read ↗

Development of a metastasis-related genes prognostic model for colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.