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Article

Integrating TYMS, KRAS and BRAF testing in patients with metastatic colorectal cancer.

World journal of gastroenterology - 28 Aug 2017

Ntavatzikos Anastasios, Spathis Aris, Patapis Paul, Machairas Nikolaos, Peros George, Konstantoudakis Stefanos, Leventakou Danai, Panayiotides Ioannis G, Karakitsos Petros, Koumarianou Anna

Abstract excerpt

AIM: To investigate the impact of thymidylate synthase (TYMS), KRAS and BRAF in the survival of metastatic colorectal cancer (mCRC) patients treated with chemotherapy. METHODS: Clinical data were collected retrospectively from records of consecutive patients with mCRC treated with fluoropyrimidine-based chemotherapy from 1/2005 to 1/2007. Formalin-fixed paraffin-embedded tissues were retrieved for analysis. TYMS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28932083
DOI: 10.3748/wjg.v23.i32.5913
PMCID: PMC5583576

Genes

TYMS
KRAS
BRAF

Provenance

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