Article
KIF17 mediates the learning and memory impairment in offspring induced by maternal exposure to propofol during middle pregnancy.
Molecular medicine reports - 1 Apr 2018
Wu Liuqing, Wang Shengqiang, Feng Yunlin, Zhao Weihong, Zuo Wei, Zhong Liang, Lin Jiamei, Zhao Weilu, Luo Foquan
Abstract excerpt
Preclinical studies suggest that propofol may cause neuronal injury to the developing brain. A previous study demonstrated that, in a rat model, maternal exposure to propofol during early or late pregnancy caused learning and memory impairment in the offspring. However, whether propofol exposure during middle pregnancy can cause long‑term behavioral deficits in the offspring remains to be elucidated....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.