Article
Single nucleotide polymorphisms in the 3'UTR of VPAC-1 cooperate in modulating gene expression and impact differently on the interaction with miR525-5p.
PloS one - 1 Jan 2014
Paladini Fabiana, Porciello Nicla, Camilli Giorgio, Tuncer Sinem, Cocco Elisa, Fiorillo Maria Teresa, Sorrentino Rosa
Abstract excerpt
Complex immune and neurodegenerative disorders are the result of multiple interactions between common genetic variations having, individually, a weak effect on the disease susceptibility or resistance. Interestingly, some genes have been found to be associated with more than one disease although not necessarily the same SNPs are involved. In this context, single nucleotide polymorphisms in the 3'UTR region of...
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