Article
Common genetic variants in the FETUB locus, genetically predicted fetuin-B levels, and risk of insulin resistance in obese Chinese adults.
Medicine - 1 Dec 2017
Li Zhibin, Liu Changqin, Shi Xiulin, Chen Zheng, Wang Dongmei, Li Long, Tu Yichang, Lin Mingzhu, Liu Suhuan, Yang Shuyu, Li Xuejun
Abstract excerpt
Elevated serum fetuin-B is suggested to be associated with insulin resistance, but it is unknown if this association is causal. The aim of this study was to explore the potential causal relationship between fetuin-B and insulin resistance.We used Mendelian randomization analysis by incorporating information of genetic variants in FETUB and serum fetuin-B concentrations with insulin resistance in 1148 obese...
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