Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians.

Human molecular genetics - 1 Jul 2017

Nongmaithem Suraj S, Joglekar Charudatta V, Krishnaveni Ghattu V, Sahariah Sirazul A, Ahmad Meraj, Ramachandran Swetha, Gandhi Meera, Chopra Harsha, Pandit Anand, Potdar Ramesh D, H D Fall Caroline, Yajnik Chittaranjan S, Chandak Giriraj R

Abstract excerpt

Vitamin B12 is an important cofactor in one-carbon metabolism whose dysregulation is associated with various clinical conditions. Indians have a high prevalence of B12 deficiency but little is known about the genetic determinants of circulating B12 concentrations in Indians. We performed a genome-wide association study in 1001 healthy participants in the Pune Maternal Nutrition Study (PMNS), replication studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Fucosyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Linkage Disequilibrium

Share to Promoter Regions, Genetic

Share to Vitamin B 12

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 28334792
DOI: 10.1093/hmg/ddx071
PMCID: PMC5886186

Genes

FUT6
CUBN
FUT2
MMAA
TCN1
TCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians.PMID 28334792Read ↗

GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in IndiansSemantic proximity Read ↗

Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.Semantic proximity Read ↗

Common variants of FUT2 are associated with plasma vitamin B12 levels.Semantic proximity Read ↗

Common variant in FUT2 gene is associated with levels of vitamin B(12) in Indian population.Semantic proximity Read ↗

Common and ethnic-specific genetic determinants of hemoglobin concentration between Taiwanese Han Chinese and European Whites: findings from comparative two-stage genome-wide association studies.Semantic proximity Read ↗

Genome-Wide Association Study Identifies Genetic Polymorphisms for Folate-Related Biomarkers in Chinese Preconception Women.Semantic proximity Read ↗

Transcriptional Downregulation by Nucleotide Substitution with the Minor Allele of rs3760776 Located in the Promoter of FUT6 Gene.Semantic proximity Read ↗

Functional Iron-Transport Genes-TF and TMPRSS6-As Genetic Determinants of Transferrin and Fasting Glucose in a Kazakh Adult Cohort: A Whole-Exome Sequencing Pilot Study.Semantic proximity Read ↗

Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.Semantic proximity Read ↗

Genetic Architecture of Vitamin B12 and Folate Levels Uncovered Applying Deeply Sequenced Large DatasetsSemantic proximity Read ↗

FUT2 nonfunctional variant: a "missing link" between genes and environment in type 1 diabetes?Semantic proximity Read ↗

Association of common TMPRSS6 and TF gene variants with hepcidin and iron status in healthy rural Gambians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.