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Article

The Ewing Sarcoma Secretome and Its Response to Activation of Wnt/beta-catenin Signaling

31 Jan 2018

Abstract excerpt

Tumor: tumor microenvironment (TME) interactions are critical for tumor progression and the composition and structure of the local extracellular matrix (ECM) are key determinants of tumor metastasis. We recently reported that activation of Wnt/beta-catenin signaling in Ewing sarcoma cells induces widespread transcriptional changes that are associated with acquisition of a metastatic tumor phenotype....

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PMID: 29386236
DOI: 10.1074/mcp.ra118.000596

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