Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

30 Jan 2018

Abstract excerpt

Viral RNA-dependent RNA polymerases (RdRps) play a central role not only in viral replication, but also in the genetic evolution of viral RNAs. After binding to an RNA template and selecting 5′-triphosphate ribonucleosides, viral RdRps synthesize an RNA copy according to Watson-Crick base-pairing rules. The copy process sometimes deviates from both the base-pairing rules specified by the template and the natural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to HIV Research and Treatment
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29385764
DOI: 10.3390/v10020059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA PolymerasesPMID 29385764Read ↗

A Structure-Function Diversity Survey of the RNA-Dependent RNA Polymerases From the Positive-Strand RNA VirusesSemantic proximity Read ↗

A Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae FamilySemantic proximity Read ↗

Crystal structure of a tick-borne flavivirus RNA-dependent RNA polymerase suggests a host adaptation hotspot in RNA virusesSemantic proximity Read ↗

Fidelity Variants and RNA Quasispecies.Semantic proximity Read ↗

Novel ribonucleotide discrimination in the RNA polymerase-like two-barrel catalytic core of Family D DNA polymerases.Semantic proximity Read ↗

A novel mechanism of enhanced transcription activity and fidelity for influenza A viral RNA-dependent RNA polymerase.Semantic proximity Read ↗

Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA PolymerasesSemantic proximity Read ↗

An induced-fit de novo initiation mechanism suggested by a pestivirus RNA-dependent RNA polymerase.Semantic proximity Read ↗

Sequential structures provide insights into the fidelity of RNA replicationSemantic proximity Read ↗

Molecular basis of fidelity of DNA synthesis and nucleotide specificity of retroviral reverse transcriptases.Semantic proximity Read ↗

Slow PPi release enhances fidelity of the SARS-CoV-2 RNA dependent RNA polymerase.Semantic proximity Read ↗

Identification of a Conserved RNA-dependent RNA Polymerase (RdRp)-RNA Interface Required for Flaviviral ReplicationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.