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Article

Molecular basis of fidelity of DNA synthesis and nucleotide specificity of retroviral reverse transcriptases.

Progress in nucleic acid research and molecular biology - 1 Jan 2002

Menéndez-Arias Luis

Abstract excerpt

Reverse transcription involves the conversion of viral genomic RNAinto proviral double-stranded DNA that integrates into the host cell genome. Cellular DNA polymerases replicate the integrated viral DNA and RNA polymerase II transcribes the proviral DNA into RNA genomes that are packaged into virions. Although mutations can be introduced at any of these replication steps, reverse transcriptase (RT) errors play a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Recombination, Genetic

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Share to Sequence Homology, Amino Acid

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Source

Identifiers

PMID: 12102562
DOI: 10.1016/s0079-6603(02)71042-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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