Article
The Effects of Inflammation on Alpha 1 Antitrypsin Levels in a National Screening Cohort.
COPD - 1 Feb 2018
Sanders Christopher L, Ponte Amy, Kueppers Friedrich
Abstract excerpt
Alpha 1 Antitrypsin (AAT) is a highly polymorphic serum protein. Several genetic variants are associated with varying degrees of decreased serum levels; however, these levels can rise in response to infection, inflammation, injury and estrogen levels. Although the effect of inflammation is well established, it has never been studied quantitatively with respect to specific genotypes in a large representative...
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