Article
SARS-CoV-2 infection in alpha1-antitrypsin deficiency.
Respiratory medicine - 1 Aug 2021
Schneider Carolin V, Strnad Pavel
Abstract excerpt
Alpha1-antitrypsin deficiency arises due to mutations in alpha1-antitrypsin (AAT) gene and represents the most prominent genetic predisposition to chronic obstructive pulmonary disease and emphysema. Since AAT plays important immunomodulatory and tissue-protective roles and since it was suggested to protect from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, we assessed this association...
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