Article
C reactive protein and alpha1-antitrypsin: relationship between levels and gene variants.
Translational research : the journal of laboratory and clinical medicine - 1 Jun 2011
Ottaviani Stefania, Gorrini Marina, Scabini Roberta, Kadija Zamir, Paracchini Elena, Mariani Francesca, Ferrarotti Ilaria, Luisetti Maurizio
Abstract excerpt
The first step in laboratory diagnosis of alpha1-antitrypsin deficiency (AATD) is the determination of alpha1-antitrypsin (AAT) serum levels; these levels in turn are influenced by the inflammatory status. C reactive protein (CRP) has been proposed as a marker of systemic inflammation. Single nucleotide polymorphisms (SNPs) in the CRP gene have been associated with differences in baseline CRP levels. The purpose...
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