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Article

Pharmacogenetics of Risperidone-Induced Insulin Resistance in Children and Adolescents with Autism Spectrum Disorder.

Basic & clinical pharmacology & toxicology - 1 Jul 2018

Sukasem Chonlaphat, Vanwong Natchaya, Srisawasdi Pornpen, Ngamsamut Nattawat, Nuntamool Nopphadol, Hongkaew Yaowaluck, Puangpetch Apichaya, Chamkrachangpada Bhunnada, Limsila Penkhae

Abstract excerpt

The purpose of this study was to explore the association of genetic polymorphism of genes related to pharmacokinetics or pharmacodynamics with insulin resistance in children and adolescents with autism spectrum disorder (ASD) and treated with risperidone. All 89 subjects underwent measurement of fasting blood glucose and insulin levels, body-weight and height. Genotyping was performed by TaqMan real-time...

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Source

Identifiers

PMID: 29369497
DOI: 10.1111/bcpt.12970

Genes

BDNF
ABCB1
DRD2
LEP
GHRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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