Article
The effect of the Taq1A variant in the dopamine D₂ receptor gene and common CYP2D6 alleles on prolactin levels in risperidone-treated boys.
Pharmacogenetics and genomics - 1 Sept 2013
Roke Yvette, van Harten Peter N, Franke Barbara, Galesloot Tessel E, Boot Annemieke M, Buitelaar Jan K
Abstract excerpt
OBJECTIVE: To investigate the effect of the Taq1A variant in the Dopamine D2 receptor gene (DRD2) and common functional genetic variants in the cytochrome P450 2D6 gene (CYP2D6) on prolactin levels in risperidone-treated boys with autism spectrum disorders and disruptive behavior disorders. METHODS: Forty-seven physically healthy 10-year-old to 19-year-old boys with autism spectrum disorders and/or disruptive...
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