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Article

Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in neuroplasticity and the risk for alcohol dependence.

Drug and alcohol dependence - 1 Apr 2015

Forero Diego A, López-León Sandra, Shin Hyoung Doo, Park Byung Lae, Kim Dai-Jin

Abstract excerpt

BACKGROUND: Alcohol-related problems have a large impact on human health, accounting for around 4% of deaths and 4.5% of disability-adjusted life-years around the world. Genetic factors could explain a significant fraction of the risk for alcohol dependence (AD). Recent meta-analyses have found significant pooled odds ratios (ORs) for variants in the ADH1B, ADH1C, DRD2 and HTR2A genes. METHODS: In the present...

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Brain-Derived Neurotrophic Factor
Monoamine Oxidase
Neuronal Plasticity
Receptors, Dopamine D1
Receptors, Dopamine D3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Dopamine D4

Receptors, N-Methyl-D-Aspartate

Synaptic Transmission

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Identifiers

PMID: 25660313
DOI: 10.1016/j.drugalcdep.2015.01.017

Genes

BDNF
DRD1
DRD3
DRD4
MAOA
DRD2

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