Article
Family-based study of brain-derived neurotrophic factor (BDNF) gene polymorphism in alcohol dependence.
Pharmacological reports : PR - 1 Jan 2000
Grzywacz Anna, Samochowiec Agnieszka, Ciechanowicz Andrzej, Samochowiec Jerzy
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) belongs to a family of proteins related to the nerve growth factor family, which are responsible for the proliferation, survival and differentiation of neurons. BDNF is thought to be involved in the pathogenesis of bipolar disorder, schizophrenia, eating disorders and addiction. We hypothesize that a functionally relevant polymorphism of the BDNF gene promoter may be...
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