Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Not Everyone Fits the Mold: Intratumor and Intertumor Heterogeneity and Innovative Cancer Drug Design and Development.

Omics : a journal of integrative biology - 1 Jan 2018

Dzobo Kevin, Senthebane Dimakatso Alice, Thomford Nicholas Ekow, Rowe Arielle, Dandara Collet, Parker M Iqbal

Abstract excerpt

Disruptive innovations in medicine are game-changing in nature and bring about radical shifts in the way we understand human diseases, their treatment, and/or prevention. Yet, disruptive innovations in cancer drug design and development are still limited. Therapies that cure all cancer patients are in short supply or do not exist at all. Chief among the causes of this predicament is drug resistance, a mechanism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clonal Evolution
Share to Disease Management

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Design

Share to Drug Development

Share to Genetic Heterogeneity

Share to Molecular Targeted Therapy

Share to Stochastic Processes

Share to Tumor Microenvironment

Source

Identifiers

PMID: 29356626
DOI: 10.1089/omi.2017.0174

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Not Everyone Fits the Mold: Intratumor and Intertumor Heterogeneity and Innovative Cancer Drug Design and Development.PMID 29356626Read ↗

Tumor heterogeneity reshapes the tumor microenvironment to influence drug resistanceSemantic proximity Read ↗

Intratumor Heterogeneity: The Rosetta Stone of Therapy Resistance.Semantic proximity Read ↗

From Chaos to Opportunity: Decoding Cancer Heterogeneity for Enhanced Treatment StrategiesSemantic proximity Read ↗

From complexity to clarity: unravelling tumor heterogeneity through the lens of tumor microenvironment for innovative cancer therapySemantic proximity Read ↗

Clinical implications of intratumor heterogeneity: challenges and opportunities.Semantic proximity Read ↗

Application of single-cell and spatial omics in deciphering cellular hallmarks of cancer drug response and resistanceSemantic proximity Read ↗

Tumor heterogeneity: preclinical models, emerging technologies, and future applicationsSemantic proximity Read ↗

Tumor heterogeneity and personalized cancer medicine: are we being outnumbered?Semantic proximity Read ↗

Intratumoral Heterogeneity: From Diversity Comes ResistanceSemantic proximity Read ↗

A Pan-Cancer Single-Cell Compendium of Intratumoural HeterogeneitySemantic proximity Read ↗

Navigating the Challenge of Tumor Heterogeneity in Cancer TherapySemantic proximity Read ↗

[Intratumor heterogeneity, a Darwinian stumbling block towards personalized medicine?].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.