Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Navigating the Challenge of Tumor Heterogeneity in Cancer Therapy

1 Feb 2014

Abstract excerpt

The future of cancer treatment lies in personalized strategies designed to specifically target tumorigenic cell populations present in an individual. Although recent advances in directed therapies have greatly improved patient outcomes in some cancers, intuitive drug design is proving more difficult than expected owing largely to the complexity of human cancers. Intratumoral heterogeneity, the presence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Lung Cancer Treatments and Mutations
Share to Mathematical Biology Tumor Growth

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24501303
DOI: 10.1158/2159-8290.cd-13-1042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Navigating the Challenge of Tumor Heterogeneity in Cancer TherapyPMID 24501303Read ↗

Tumor heterogeneity and personalized cancer medicine: are we being outnumbered?Semantic proximity Read ↗

Tumor heterogeneity: preclinical models, emerging technologies, and future applicationsSemantic proximity Read ↗

Tumor heterogeneity reshapes the tumor microenvironment to influence drug resistanceSemantic proximity Read ↗

From Chaos to Opportunity: Decoding Cancer Heterogeneity for Enhanced Treatment StrategiesSemantic proximity Read ↗

Heterogeneity in CancerSemantic proximity Read ↗

Toward understanding and exploiting tumor heterogeneitySemantic proximity Read ↗

Not Everyone Fits the Mold: Intratumor and Intertumor Heterogeneity and Innovative Cancer Drug Design and Development.Semantic proximity Read ↗

The challenges of tumor genetic diversity.Semantic proximity Read ↗

Intratumoral Heterogeneity: From Diversity Comes ResistanceSemantic proximity Read ↗

A unifying framework disentangles genetic, epigenetic, and stochastic sources of drug-response variability in an <i>in vitro</i> model of tumor heterogeneitySemantic proximity Read ↗

Characterization of cancer genomic heterogeneity by next-generation sequencing advances precision medicine in cancer treatmentSemantic proximity Read ↗

Tumor Heterogeneity and Personalized MedicineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.