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Article

Serum HBV DNA plus RNA shows superiority in reflecting the activity of intrahepatic cccDNA in treatment-naïve HBV-infected individuals.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jan 2000

Huang Hongxin, Wang Jie, Li Weijie, Chen Ran, Chen Xiangmei, Zhang Fengmin, Xu Dongping, Lu Fengmin

Abstract excerpt

BACKGROUND: Both serum hepatitis B virus (HBV) DNA and RNA can reflect intrahepatic covalently closed circular DNA (cccDNA) activity. However, correlations among viral markers haven't been fully explored. OBJECTIVES: Here we investigated the correlations between serum HBV RNA and other viral markers in acute hepatitis B patients and treatment-naïve chronic HBV-infected individuals. STUDY DESIGN: The serum viral...

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Identifiers

PMID: 29353073
DOI: 10.1016/j.jcv.2017.12.016

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