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Article

Use of Single-Nucleotide Polymorphisms and Mammographic Density Plus Classic Risk Factors for Breast Cancer Risk Prediction.

JAMA oncology - 1 Apr 2018

van Veen Elke M, Brentnall Adam R, Byers Helen, Harkness Elaine F, Astley Susan M, Sampson Sarah, Howell Anthony, Newman William G, Cuzick Jack, Evans D Gareth R

Abstract excerpt

IMPORTANCE: Single-nucleotide polymorphisms (SNPs) have demonstrated an association with breast cancer susceptibility, but there is limited evidence on how to incorporate them into current breast cancer risk prediction models. OBJECTIVE: To determine whether a panel of 18 SNPs (SNP18) may be used to predict breast cancer in combination with classic risk factors and mammographic density. DESIGN, SETTING, AND...

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Identifiers

PMID: 29346471
DOI: 10.1001/jamaoncol.2017.4881
PMCID: PMC5885189

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