Article
Molecular portraits of clear cell ovarian and endometrial carcinoma with comparison to clear cell renal cell carcinoma.
Gynecologic oncology - 1 Feb 2023
Ackroyd Sarah A, Arguello David, Ramos Pilar, Mahdi Haider, ElNaggar Adam, Winer Ira, Holloway Rob, Krivak Thomas, Jones Nathaniel, Turner Valerie Galvan, Herzog Thomas, Chu Christina, Brown Jubilee, Mantia-Smaldone Gina
Abstract excerpt
OBJECTIVE: Advanced clear cell gynecologic malignancies remain among the most challenging diseases to manage. We evaluated ovarian and endometrial clear cell carcinoma (OCCC and ECCC) specimens using comprehensive sequencing technology to identify mutational targets and compared their molecular profiles to histologically similar clear cell renal cell carcinoma (ccRCC). METHODS: Using next-generation sequencing...
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