Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Poxvirus Genome Uncoating and DNA Replication Factors with Mutually Redundant Roles

18 Jan 2018

Abstract excerpt

ABSTRACT Genome uncoating is essential for replication of most viruses. For poxviruses, the process is divided into two stages: removal of the envelope, allowing early gene expression, and breaching of the core wall, allowing DNA release, replication, and late gene expression. Subsequent studies showed that the host proteasome and the viral D5 protein, which has an essential role in DNA replication, are required...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to Poxvirus research and outbreaks
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29343579
DOI: 10.1128/jvi.02152-17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Poxvirus Genome Uncoating and DNA Replication Factors with Mutually Redundant RolesPMID 29343579Read ↗

Ancient Gene Capture and Recent Gene Loss Shape the Evolution of Orthopoxvirus-Host Interaction GenesSemantic proximity Read ↗

Predicted poxvirus FEN1-like nuclease required for homologous recombination, double-strand break repair and full-size genome formation.Semantic proximity Read ↗

Poxvirus Exploitation of the Ubiquitin-Proteasome SystemSemantic proximity Read ↗

Vaccinia Virus A6 Is a Two-Domain Protein Requiring a Cognate N-Terminal Domain for Full Viral Membrane Assembly Activity.Semantic proximity Read ↗

Vaccinia Virus C9 Ankyrin Repeat/F-Box Protein Is a Newly Identified Antagonist of the Type I Interferon-Induced Antiviral StateSemantic proximity Read ↗

Deletion of the Vaccinia Virus B1 Kinase Reveals Essential Functions of This Enzyme Complemented Partly by the Homologous Cellular Kinase VRK2Semantic proximity Read ↗

Poxvirus Protein MC132 from Molluscum Contagiosum Virus Inhibits NF-κB Activation by Targeting p65 for DegradationSemantic proximity Read ↗

Evolutionary Variation of Poxvirus Genome ArchitectureSemantic proximity Read ↗

Identification of nucleotide-level changes impacting gene content and genome evolution in orthopoxviruses.Semantic proximity Read ↗

Enigmatic origin of the poxvirus membrane from the endoplasmic reticulum shown by 3D imaging of vaccinia virus assembly mutants.Semantic proximity Read ↗

Replicating poxviruses for human cancer therapySemantic proximity Read ↗

Vaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.