Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Poxvirus Protein MC132 from Molluscum Contagiosum Virus Inhibits NF-κB Activation by Targeting p65 for Degradation

4 Jun 2015

Abstract excerpt

ABSTRACT Molluscum contagiosum virus (MCV) is unique in being the only known extant, human-adapted poxvirus, yet to date, it is very poorly characterized in terms of host-pathogen interactions. MCV causes persistent skin lesions filled with live virus, but these are generally immunologically silent, suggesting the presence of potent inhibitors of human antiviral immunity and inflammation. Fewer than five MCV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to interferon and immune responses
Share to Poxvirus research and outbreaks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26041281
DOI: 10.1128/jvi.00799-15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Poxvirus Protein MC132 from Molluscum Contagiosum Virus Inhibits NF-κB Activation by Targeting p65 for DegradationPMID 26041281Read ↗

Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase ActivationSemantic proximity Read ↗

An immune-suppressing protein in human endogenous retrovirusesSemantic proximity Read ↗

Genome Sequence of a Human Tumorigenic Poxvirus: Prediction of Specific Host Response-Evasion GenesSemantic proximity Read ↗

Poxvirus Driven Human Diseases and Emerging TherapeuticsSemantic proximity Read ↗

Inhibition of interferon gene activation by death-effector domain-containing proteins from the molluscum contagiosum virusSemantic proximity Read ↗

The unique immune evasion mechanisms of the mpox virus and their implication for developing new vaccines and immunotherapiesSemantic proximity Read ↗

High content screening and computational prediction reveal viral genes that suppress innate immune responseSemantic proximity Read ↗

A poxvirus ankyrin protein LSDV012 inhibits IFIT1 in a host-species-specific manner by compromising its RNA binding abilitySemantic proximity Read ↗

The nuclear localization signal of monkeypox virus protein P2 orthologue is critical for inhibition of IRF3-mediated innate immunitySemantic proximity Read ↗

Merkel Cell Polyomavirus Infection Induces an Antiviral Innate Immune Response in Human Dermal FibroblastsSemantic proximity Read ↗

A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded VpxSemantic proximity Read ↗

Identification of Poxvirus Genome Uncoating and DNA Replication Factors with Mutually Redundant RolesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.