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Poxvirus Exploitation of the Ubiquitin-Proteasome System

19 Oct 2010

Abstract excerpt

Ubiquitination plays a critical role in many cellular processes. A growing number of viruses have evolved strategies to exploit the ubiquitin-proteasome system, including members of the Poxviridae family. Members of the poxvirus family have recently been shown to encode BTB/kelch and ankyrin/F-box proteins that interact with cullin-3 and cullin-1 based ubiquitin ligases, respectively. Multiple members of the...

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PMID: 21994622
DOI: 10.3390/v2102356

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