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Article

Identification of nucleotide-level changes impacting gene content and genome evolution in orthopoxviruses.

Journal of virology - 1 Dec 2014

Hatcher Eneida L, Hendrickson Robert Curtis, Lefkowitz Elliot J

Abstract excerpt

UNLABELLED: Poxviruses are composed of large double-stranded DNA (dsDNA) genomes coding for several hundred genes whose variation has supported virus adaptation to a wide variety of hosts over their long evolutionary history. Comparative genomics has suggested that the Orthopoxvirus genus in particular has undergone reductive evolution, with the most recent common ancestor likely possessing a gene complement...

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Identifiers

PMID: 25231308
DOI: 10.1128/JVI.02015-14
PMCID: PMC4248964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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