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Article

Analysis of copy number loss of the ErbB4 receptor tyrosine kinase in glioblastoma.

PloS one - 1 Jan 2018

Jones DeAnalisa C, Scanteianu Adriana, DiStefano Matthew, Bouhaddou Mehdi, Birtwistle Marc R

Abstract excerpt

Current treatments for glioblastoma multiforme (GBM)-an aggressive form of brain cancer-are minimally effective and yield a median survival of 14.6 months and a two-year survival rate of 30%. Given the severity of GBM and the limitations of its treatment, there is a need for the discovery of novel drug targets for GBM and more personalized treatment approaches based on the characteristics of an individual's...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29342193
DOI: 10.1371/journal.pone.0190664
PMCID: PMC5771580

Genes

ERBB4
EGFR
NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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