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Article

Expression of the lux genes in Streptococcus pneumoniae modulates pilus expression and virulence.

PloS one - 1 Jan 2018

Herbert Jenny A, Mitchell Andrea M, Ritchie Ryan, Ma Jiangtao, Ross-Hutchinson Kirsty, Mitchell Timothy J

Abstract excerpt

Bioluminescence has been harnessed for use in bacterial reporter systems and for in vivo imaging of infection in animal models. Strain Xen35, a bioluminescent derivative of Streptococcus pneumoniae serotype 4 strain TIGR4 was previously constructed for use for in vivo imaging of infections in animal models. We have shown that strain Xen35 is less virulent than its parent TIGR4 and that this is associated with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29342160
DOI: 10.1371/journal.pone.0189426
PMCID: PMC5771582

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