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Article

Site-Specific Mutations of GalR Affect Galactose Metabolism in Streptococcus pneumoniae.

Journal of bacteriology - 7 Dec 2020

McLean Kimberley T, Tikhomirova Alexandra, Brazel Erin B, Legendre Salomé, Haasbroek Gian, Minhas Vikrant, Paton James C, Trappetti Claudia

Abstract excerpt

Streptococcus pneumoniae (the pneumococcus) is a formidable human pathogen that is capable of asymptomatically colonizing the nasopharynx. Progression from colonization to invasive disease involves adaptation to distinct host niches, which vary markedly in the availability of key nutrients such as sugars. We previously reported that cell-cell signaling via the autoinducer 2 (AI-2)/LuxS quorum-sensing system...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33046563
DOI: 10.1128/JB.00180-20
PMCID: PMC7723958

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