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Article

The core promoter of the capsule operon of Streptococcus pneumoniae is necessary for colonization and invasive disease.

Infection and immunity - 1 Feb 2014

Shainheit Mara G, Mulé Matthew, Camilli Andrew

Abstract excerpt

Streptococcus pneumoniae is a commensal of the human nasopharynx but can cause invasive diseases, including otitis media, pneumonia, sepsis, and meningitis. The capsular polysaccharide (capsule) is a critical virulence factor required for both asymptomatic colonization and invasive disease, yet the expression level is different in each anatomical site. During colonization, reduced levels of capsule promote...

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Share to Bacteremia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24478084
DOI: 10.1128/IAI.01289-13
PMCID: PMC3911406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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