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Cell-free DNA from ascites identifies clinically relevant variants and tumour evolution in patients with advanced ovarian cancer

2024-03-15

Abstract excerpt

<h4>Background: </h4> The emergence of targeted therapies and predictive biomarkers is transforming the ovarian cancer treatment paradigm. However, the demand for high quality, tumour-enriched samples for biomarker profiling can be limited by access to adequate tissue samples. The use of cell-free DNA (cfDNA) in ascites presents a potential solution to this clinical challenge. Methods A unique set of sequential as...

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Literature Corpus work
870dad6a-4670-5ffe-9a8f-a5cf8ef1274f
DOI
10.1101/2024.03.09.24303840
Open publication

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Cell-free DNA from ascites identifies clinically relevant variants and tumour evolution in patients with advanced ovarian cancerDOI 10.1101/2024.03.09.24303840
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