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Article

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies.

Trends in cell biology - 1 Oct 2011

Grabrucker Andreas M, Schmeisser Michael J, Schoen Michael, Boeckers Tobias M

Abstract excerpt

Intact synaptic homeostasis is a fundamental prerequisite for a healthy brain. Thus, it is not surprising that altered synaptic morphology and function are involved in the molecular pathogenesis of so-called synaptopathies including autism, schizophrenia (SCZ) and Alzheimer's disease (AD). Intriguingly, various recent studies revealed a crucial role of postsynaptic ProSAP/Shank scaffold proteins in all of the...

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Identifiers

PMID: 21840719
DOI: 10.1016/j.tcb.2011.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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