Exploring the association of rs10490924 polymorphism with age-related macular degeneration: An in silico approach.

doi:10.1016/j.jmgm.2017.12.023

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Article

Exploring the association of rs10490924 polymorphism with age-related macular degeneration: An in silico approach.

Journal of molecular graphics & modelling - 1 Mar 2018

Jahanfar Farhad, Hamishehkar Hamed

Abstract excerpt

The polymorphism rs10490924 (A69S) in the age-related maculopathy susceptibility 2 (ARMS2) gene is highly associated with age-related macular degeneration, which is the leading cause of blindness among the elderly population. ARMS2 gene encodes a putative small (11 kDa) protein, which the function and localization of the ARMS2 protein remain under debate. For a better understanding of functional impacts of A69S...

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PMID: 29316486
DOI: 10.1016/j.jmgm.2017.12.023

Genes

ARMS2

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