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Article

Genetic variants in COL13A1, ADIPOQ and SAMM50, in addition to the PNPLA3 gene, confer susceptibility to elevated transaminase levels in an admixed Mexican population.

Experimental and molecular pathology - 1 Feb 2018

Larrieta-Carrasco Elena, Flores Yvonne N, Macías-Kauffer Luis R, Ramírez-Palacios Paula, Quiterio Manuel, Ramírez-Salazar Eric G, León-Mimila Paola, Rivera-Paredez Berenice, Cabrera-Álvarez Guillermo, Canizales-Quinteros Samuel, Zhang Zuo-Feng, López-Pérez Tania V, Salmerón Jorge, Velázquez-Cruz Rafael

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of extra fat in liver cells not caused by alcohol. Elevated transaminase levels are common indicators of liver disease, including NAFLD. Previously, we demonstrated that PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), and GCKR (rs780094) are associated with elevated transaminase levels in overweight/obese Mexican adults. We investigated...

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Source

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Identifiers

PMID: 29307798
DOI: 10.1016/j.yexmp.2018.01.001
PMCID: PMC6027652

Genes

PNPLA3
ADIPOQ
SAMM50
GCKR
LYPLAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genetic variants in COL13A1, ADIPOQ and SAMM50, in addition to the PNPLA3 gene, confer susceptibility to elevated transaminase levels in an admixed Mexican population.PMID 29307798Read ↗

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