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Autoimmunity and Cancer—Two Sides of the Same Coin

13 May 2022

Abstract excerpt

Autoimmune disease results from the immune response against self-antigens, while cancer develops when the immune system does not respond to malignant cells. Thus, for years, autoimmunity and cancer have been considered as two separate fields of research that do not have a lot in common. However, the discovery of immune checkpoints and the development of anti-cancer drugs targeting PD-1 (programmed cell death...

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PMID: 35634292
DOI: 10.3389/fimmu.2022.793234

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