Article
Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.
British journal of cancer - 1 Jan 2018
Mikropoulos Christos, Selkirk Christina G Hutten, Saya Sibel, Bancroft Elizabeth, Vertosick Emily, Dadaev Tokhir, Brendler Charles, Page Elizabeth, Dias Alexander, Evans D Gareth, Rothwell Jeanette, Maehle Lovise, Axcrona Karol, Richardson Kate, Eccles Diana, Jensen Thomas, Osther Palle J, van Asperen Christi J, Vasen Hans, Kiemeney Lambertus A, Ringelberg Janneke, Cybulski Cezary, Wokolorczyk Dominika, Hart Rachel, Glover Wayne, Lam Jimmy, Taylor Louise, Salinas Monica, Feliubadaló Lidia, Oldenburg Rogier, Cremers Ruben, Verhaegh Gerald, van Zelst-Stams Wendy A, Oosterwijk Jan C, Cook Jackie, Rosario Derek J, Buys Saundra S, Conner Tom, Domchek Susan, Powers Jacquelyn, Ausems Margreet Gem, Teixeira Manuel R, Maia Sofia, Izatt Louise, Schmutzler Rita, Rhiem Kerstin, Foulkes William D, Boshari Talia, Davidson Rosemarie, Ruijs Marielle, Helderman-van den Enden Apollonia Tjm, Andrews Lesley, Walker Lisa, Snape Katie, Henderson Alex, Jobson Irene, Lindeman Geoffrey J, Liljegren Annelie, Harris Marion, Adank Muriel A, Kirk Judy, Taylor Amy, Susman Rachel, Chen-Shtoyerman Rakefet, Pachter Nicholas, Spigelman Allan, Side Lucy, Zgajnar Janez, Mora Josefina, Brewer Carole, Gadea Neus, Brady Angela F, Gallagher David, van Os Theo, Donaldson Alan, Stefansdottir Vigdis, Barwell Julian, James Paul A, Murphy Declan, Friedman Eitan, Nicolai Nicola, Greenhalgh Lynn, Obeid Elias, Murthy Vedang, Copakova Lucia, McGrath John, Teo Soo-Hwang, Strom Sara, Kast Karin, Leongamornlert Daniel A, Chamberlain Anthony, Pope Jenny, Newlin Anna C, Aaronson Neil, Ardern-Jones Audrey, Bangma Chris, Castro Elena, Dearnaley David, Eyfjord Jorunn, Falconer Alison, Foster Christopher S, Gronberg Henrik, Hamdy Freddie C, Johannsson Oskar, Khoo Vincent, Lubinski Jan, Grindedal Eli Marie, McKinley Joanne, Shackleton Kylie, Mitra Anita V, Moynihan Clare, Rennert Gad, Suri Mohnish, Tricker Karen, Moss Sue, Kote-Jarai Zsofia, Vickers Andrew, Lilja Hans, Helfand Brian T, Eeles Rosalind A
Abstract excerpt
BACKGROUND: Prostate-specific antigen (PSA) and PSA-velocity (PSAV) have been used to identify men at risk of prostate cancer (PrCa). The IMPACT study is evaluating PSA screening in men with a known genetic predisposition to PrCa due to BRCA1/2 mutations. This analysis evaluates the utility of PSA and PSAV for identifying PrCa and high-grade disease in this cohort. METHODS: PSAV was calculated using logistic...