Article
Impact of heart-specific disruption of the circadian clock on systemic glucose metabolism in mice.
Chronobiology international - 1 Apr 2018
Nakao Tomomi, Kohsaka Akira, Otsuka Tsuyoshi, Thein Zaw Lin, Le Hue Thi, Waki Hidefumi, Gouraud Sabine S, Ihara Hayato, Nakanishi Masako, Sato Fuyuki, Muragaki Yasuteru, Maeda Masanobu
Abstract excerpt
The daily rhythm of glucose metabolism is governed by the circadian clock, which consists of cell-autonomous clock machineries residing in nearly every tissue in the body. Disruption of these clock machineries either environmentally or genetically induces the dysregulation of glucose metabolism. Although the roles of clock machineries in the regulation of glucose metabolism have been uncovered in major metabolic...
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